Interaction of microsecond dual-wavelength laser radiation with soft tissues
Danil V. Pechenkin1, Arsen K. Zotov1, Yuriy A. Suchkov1, David G. Kochiev1; 1Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991, Moscow, Russia
Abstract
Laser surgery is widely used in various fields of medicine, including urology, dermatology, and oncology, as well as other clinical areas [1,2]. The effectiveness and safety of laser exposure depended on several parameters, including wavelength, pulse duration, energy density, absorption coefficient, and tissue type [3]. A promising direction in medical laser development was the use of dual-wavelength regimes combining radiation at the fundamental wavelength and its second harmonic. Such regimes were used in laser lithotripsy for fragmentation of calculi in the microsecond pulse duration range [4]. However, their application for soft biological tissues remained poorly understood due to significant differences in optical, mechanical, and thermophysical properties compared to calculi [3,5,6]. Therefore, the study of microsecond dual-wavelength laser interaction with soft tissues was of high relevance.
A dual-wavelength pulsed Nd:YAlO₃ (Nd:YAP) laser with radiation at 1080 and 540 nm was used in this work. The pulse train consisted of seven pulses with a pulse duration of 1 μs, a period of 34 μs, and a total duration of 213 μs, resulting in a total energy of 0.98 J. The energy of a single pulse was 0.14 J.
The interaction of microsecond dual-wavelength laser radiation with soft tissues was investigated experimentally. Time-resolved transmission signals were recorded through soft tissue, emission spectra from the interaction region were measured, and high-speed imaging of the interaction region was performed. The results showed specific features of dual-wavelength laser–tissue interaction, indicating shielding effects.
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3 Niemz M.H., Laser-tissue interactions: fundamentals and applications, Springer, Berlin (2004).
4 Helfmann J., Müller G., Med. Laser Appl. 16, 30–37 (2001).
5 Alagha H., Gülsoy M., J. Biomed. Opt. 21, 015007 (2016).
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Speaker
Danil Pechenkin
Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991, Moscow, Russia
Russia
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