Determination of aspartame by modified amperometric sensors

Abstract

The field of express detection is one of the most promising areas of analytical chemistry. At the same time, special attention is paid to the possibility of using various systems in the "field". One of the interesting solutions here is the use of modified sensor systems. One of the modification options is often molecularly imprinted polymers (MIP). These polymers have a number of advantages over other modifiers (for example, proteins or antibodies). Among the advantages of a number of such polymers, one can highlight their mechanical and chemical stability, which is extremely important when used in non-laboratory conditions. In this work, amperometric sensors modified with a molecularly imprinted polymer for the express determination of aspartame were developed. The issue of its safety is still one of the most discussed and controversial. It is known that aspartame can negatively affect the body when the permissible doses are exceeded, especially in people with phenylketonuria, and in 2023, the WHO recognized it as a possible carcinogen. The sensors are made by the thermal transfer method, which allows obtaining two-dimensional electrodes of almost any shape. Foil-clad glass-textolite was used as a substrate. The obtained sensors were modified with a polymer with a molecular imprint of aspartame. For this purpose, a prepolymerization mixture consisting of a copolymer of 1,2,4,5-benzene tracarboxylic acid with 4,4'-diaminodiphenyl oxide was mixed with an aqueous-alcoholic solution of aspartame, after which thermal imitation was carried out to obtain a PMO film. Then, the model solutions were analyzed under static conditions. The accuracy of the determination was assessed using the "introduced-found" method. The working range of concentrations was 10-3 g/dm3 - 1 g/dm3, the Sr value does not exceed 10%.

Speaker

Vybornyi Antony Yurievich
Voronezh State University, Voronezh
Russia

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