Cancer and cellular electromagnetic field /In memory of Jiří Pokorný/
Jan Pokorný; Institute of Physics of the Czech Academy of Sciences, Prague, Czech Republic
Abstract
An interdisciplinary framework of phenomena related to cancer development is presented, with special attention to the causes and consequences of disturbed cellular electromagnetic activity. The primary focus is on mitochondrial dysfunction (the Warburg effect), being not only a result of oncogenic mutation but also a common phenomenon connected with viral activities in a cell. Our extensive immunological study on 12,000 patients suggests chronic viral infections to be a crucial risk factor for cancer initiation. Lowered respiration connected with the Warburg effect leads to a reduced proton transfer through mitochondrial membrane and reversed polarity of ordered water layers around mitochondria. The water layers then emit electrons, resulting in damped electromagnetic activity of the affected cell. Frequency and power changes of the generated electromagnetic field result in broken communication between cells and hypothetically in reduced control over chemical reactions, with an increased probability of random genome mutations. Morphological changes then follow due to disturbed ordering forces.
According to the underlying mechanism, there are three fundamental cancer phenotypes:
(1) Warburg effect (differentiated) cancers with mitochondrial dysfunction in a cancer cell.
(2) Reverse Warburg effect (undifferentiated) cancers with a pathological cooperation between a cancer cell and associated fibroblasts. Mitochondrial dysfunction occurs in the fibroblasts.
(3) Cancers initiated by conductive nanofibres such as asbestos. Short-circuiting by the fibres leads to similar effects as damping due to mitochondrial dysfunction.
Understanding fundamental mechanisms of cancer initiation and development is a prerequisite to defining effective therapy targets as well as to developing quantitative diagnostic methods.
The talk will review most relevant scientific achievements of Jiří Pokorný (February 14, 1932 – February 23, 2024) and will be preceded by some facts of his life and scientific biography.
Speaker
Jan Pokorny
Institute of Physics of the Czech Academy of Sciences
Czech Republic
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